Advances in Renal Denervation in the Treatment of Hypertension

Preprint | 
10.55415/deep-2023-0020.v1
This is not the most recent version. There is anewer versionof this content available.
Bin Xiong
Department of Critical Care Medicine, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China;
Department of Critical Care Medicine, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China;
Shaojie Chen
Cardioangiologisches Centrum Bethanien (CCB), Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus, Akademisches Lehrkrankenhaus der Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany++Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Cardioangiologisches Centrum Bethanien (CCB), Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus, Akademisches Lehrkrankenhaus der Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany++Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Weijie Chen*
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Zhiyu Ling*
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Yuehui Yin
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

# contributed equally to this work, * Corresponding author


Abstract

Hypertension can lead to a significant increase in the risk of cardiovascular events, with a high rate of disability and mortality. It is one of the common causes of cardiovascular and cerebrovascular accidents, which seriously affect patients’ quality of life and lifespan. Currently, treatment strategies for hypertension are mainly based on medication and lifestyle interventions. The renal sympathetic nervous system plays an important role in the pathogenesis of hypertension, and catheter-based renal denervation (RDN) provides a new concept for the treatment of hypertension. In recent years, studies on RDN have been carried out worldwide. This article reviews the latest preclinical research and clinical evidence.

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  • 27 Mar 2023 11:36 Version 1
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