Transcatheter Aortic Valve Replacement for Aortic Regurgitation--A Review
Abstract
Transcatheter aortic valve replacement (TAVR) is now a widely adopted option for patients with severe symptomatic aortic stenosis from high to low surgical risk. However, aortic regurgitation (AR) is still an “off-label” indication for TAVR, especially for patients with mild or absent leaflet calcification or aortic annulus dimensions beyond the size of bioprosthesis, which causes increased risk of dislocation. With the advance of transcatheter heart valve device, the safety and efficacy of TAVR in treating patients with severe pure native AR has gained acceptance. This review examines the current evidence and clinical practice and presents the technological advancements in the device for AR.